Clinical trials have confirmed the effectiveness of PinnoThin™. Lipid Nutrition thoroughly tested PinnoThin™ in a randomized double blind cross-over trial, and the results were: PinnoThin™ can help to suppress appetite and promote a feeling of 'fullness', thus providing satiety.

The first study clearly showed that within 30-60 minutes after taking a 3 gram dose of PinnoThin™ in the form of oil or its natural metabolites the release of the satiety hormone of cholecystokinin (CCK) was significantly increased in the blood of the test subjects, compared to those who had taken a placebo. The natural metabolites of PinnoThin™ also significantly increased the release of another satiety hormone glucagon-like peptide1 (GLP1) in the blood. Both hormones send signals of satiation to the brain, and are essential in regulating food intake.

Also prospective food intake was reduced after administration of the natural metabolites of PinnoThin™. In the second study participants given these also showed a significant effect on food intake (9% reduction) and a trend on caloric intake (7% reduction).